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by Richard Laliberle,
Organic Style March 2005
Recent research shows that vitamins can stop stress and even help prevent
cancer. But too high a dose can also hurt your health. Which vitamins do you
really need? How much should you take? Our guide has the answers.
We work hard to squeeze exercise into our busy days, eat right, and avoid
taking too many aspirins or other over-the counter painkillers—yet we feel
perfectly safe popping lots of vitamin pills to help keep ourselves healthy.
Maybe we shouldn't. Last fall, researchers at Johns Hopkins University
concluded that regular high doses of vitamin E raise the risk of dying
prematurely. Taking antioxidants to fight gastrointestinal cancer might do
the same, according to a Danish study. Beta-carotene puts smokers at a
higher risk for lung cancer and death, says other research.
None of this means that we should stop taking vitamins. "Vitamins and
minerals are essential," according to James Penland, PhD, research
psychologist at the usda Agricultural Research Service's Human Nutrition
Research Center, in Grand Forks, North Dakota. "You can't live without them.
But there's an old saying that the poison is in the dose. At some point, any
nutrient can be consumed at a level that's harmful." In the case of vitamin
E, that point appears to be 400 international units (IU) per day—far lower
than the megadoses previously thought to be safe but well above the
recommended daily allowance (RDA) of 22 IU.
The smart approach: Forget the idea that more is better, and limit yourself
to a safe amount. For each nutrient, there's a healthy intake range between
not enough and too much. To make it clear where to draw the danger line, the
Institute of Medicine, which sets nutrient guidelines, now issues ULs
(tolerable upper intake levels), which are the highest doses likely to pose
no health risks.
Ideally, it's best to get your nutrients from whole foods, but since few of
us eat a perfect diet, taking a daily multivitamin is a sensible way to make
sure we meet basic nutritional needs. To help you figure all this out, we
scoured the latest research and talked to top experts to find the most
critical nutrients for a variety of conditions. Here's what—and how
much—every woman needs to help prevent those conditions:
Colds WHAT YOU NEED
Vitamin E. Despite all the hype about vitamin C over the years, studies have
failed to prove that it's effective for fighting colds.
WHAT IT DOES
The cold virus may have finally met its match: Taking 200 IU per day of
vitamin E cut the risk of catching a cold by 20 percent in a recent study of
nursing-home residents by Tufts University. Vitamin E, an antioxidant,
"helps reverse deficits in immune function that occur as you age," says
study coauthor David Hamer, MD, adjunct associate professor of nutrition at
Tufts' Jean Mayer usda Human Nutrition Research Center on Aging. Other
research suggests that no matter how old you are, getting too little E
(along with selenium, another antioxidant) may make viruses more potent in
your body.
AIM FOR 200 IU a day.
HOW TO GET IT You probably get the RDA of 22 IU if you eat foods such as salad dressing;
almonds and walnuts; leafy vegetables, like spinach; and whole grains. To
make up the difference, you need a supplement.
NEVER TAKE MORE THAN
The upper limit for vitamin E is 1,500 IU far too high in light of the
latest findings. Hamer advises taking no more than 200 IU daily.
Breast Cancer WHAT YOU NEED
Folate
WHAT IT DOES Also known as folic acid, this B vitamin is critical for healthy DNA;
getting too little is thought to increase the chances of cancer. A review
published in the Journal of the American Medical Association in June 2002
found that women who get larger amounts of folate have a lower risk of
breast cancer than women who get less. That's especially true for those who
drink moderate amounts of alcohol, which blocks folic acid from working with
DNA.
AIM FOR at least the RDA of 400 micrograms.
HOW TO GET IT
Folate is in asparagus, spinach, broccoli, black-eyed peas, and orange
juice, as well as breads and cereals containing fortified grains or flour. A
3/4-cup serving of Total cereal, for example, meets the daily requirement.
One cup of most other cereals provides at least a quarter of what you need.
A supplement can give you the rest.
NEVER TAKE MORE THAN the UL of 1,000 micrograms a day.
Stress WHAT YOU NEED Vitamin C
WHAT IT DOES
Got a make-or-break project coming up? High doses of vitamin C cause the
body to secrete lower levels of stress hormones such as cortisol, according
to research. In one study, people who took 3,000 milligrams of C a day felt
less stressed and had lower blood pressure when faced with tasks such as
public speaking and doing mental arithmetic.
AIM FOR The RDA for vitamin C is only 75 milligrams for women and 90 milligrams for
men; for stress Rx, take the megadoses used in the study.
HOW TO GET IT
Foods such as orange juice, broccoli, and red peppers provide the RDA;
you'll need to get the rest from supplements. "Vitamin C has a very good
safety profile at high doses," Guiltinan says. One reason: C is
water-soluble, meaning your body excretes what it doesn't need.
NEVER TAKE MORE THAN
Research suggests that you can take doses as high as 3,000 milligrams
without experiencing symptoms of toxicity, such as kidney stones. If a high
dose causes cramping or diarrhea, cut back by 1,000 milligrams.
Fatigue WHAT YOU NEED
Iron
WHAT IT DOES Boost your energy level by pumping a little iron into your system. While
it's widely known to help reverse the fatigue caused by anemia, iron can
also energize women who don't have anemia, possibly by increasing the
activity of enzymes that affect brain chemicals, according to a study
published in 2003 in the British Medical Journal.
AIM FOR 18 milligrams a day if you're a woman of childbearing age, because you lose
iron during your period. Postmenopausal women and men need eight milligrams.
HOW TO GET IT Eat red meat, fish, and poultry, which contain the form of iron that's most
easily absorbed, as well as spinach and legumes. Most of us get all the iron
we need from food, but premenopausal women should take a multivitamin for
insurance.
NEVER TAKE MORE THAN the UL of 45 milligrams. High doses promote inflammatory problems like
arthritis and may cause liver damage.
Heart Disease WHAT YOU NEED
B-vitamin complex
WHAT IT DOES Keep your heart healthy with the Bs, which include folate and vitamins B6
and B12. They help lower blood levels of homocysteine, an amino acid that is
thought to promote atherosclerosis.
AIM FOR no more of the Bs than the recommended daily allowance: 400 micrograms of
folic acid, 1.3 to 1.7 milligrams of vitamin B6, and 2.4 micrograms of
vitamin B12.
HOW TO GET IT Meat, poultry, and fish are good bets because they contain both B6 and B12.
But make sure to take your daily multivitamin tooit contains a form of B12
that's easier to absorb than the kind found in food.
NEVER TAKE MORE THAN
the UL for B6, 100 milligrams (extremely high doses of B6 are known to cause
nerve damage). There's not yet a UL for B12. Best strategy for now: Stick to
the RDA.
Poor Sleep WHAT YOU NEED Magnesium
WHAT IT DOES This mineral helps put you to sleep, literally. Researchers at the usda
found that getting insufficient magnesium changes electrical activity in the
brain, and those anomalies may interfere with rest. Other studies show that
lack of magnesium may disrupt normal sleep stages or contribute to such
sleep disorders as restless leg syndrome.
AIM FOR the RDA, which is 320 milligrams for women and 420 milligrams for men.
HOW TO GET IT Eat foods such as spinach, broccoli, legumes, and whole-wheat bread, and
take a multivitamin. Get as much as you want from food; supplements can
cause diarrhea. The UL for supplements is 350 milligrams.
Depression WHAT YOU NEED
Folate
WHAT IT DOES Call it the happiness pill. This B vitamin helps the brain use
mood-regulating chemicals, such as serotonin and dopamine. Researchers at
Tufts University found that people with a history of depression have lower
concentrations of folate in their blood than people who have never been
depressed.
AIM FOR the RDA of 400 micrograms.
HOW TO GET IT
Enriched grains in bread, pasta, and breakfast cereal add 80 to 200
micrograms a day to the average diet. Take a supplement to get the full
RDA some research suggests it may boost the performance of anti-depressants.
In the Tufts study, folate levels stayed low even when depression lifted,
suggesting that you should continue supplements for as long as a year
afterward.
NEVER TAKE MORE THAN 1,000 micrograms of folate.
Asthma WHAT YOU NEED Selenium
WHAT IT DOES
This mineral will help you breathe easier: In a British study, asthma was
less common in adults who had higher intakes of selenium.
AIM FOR
The RDA is 55 micrograms, though people in the study took as much as 97
micrograms.
HOW TO GET IT Selenium is in the soil in which our vegetables and grains are grown. But
soil varies widely in mineral content, so it's a good idea to take a
supplement that provides the RDA. Produce grown in areas with poor air
quality may contain little selenium. That's because ions produced by burning
fossil fuels make the soil more acidic, and that in turn keeps plants from
drawing selenium from it.
NEVER TAKE MORE THAN the UL of 400 micrograms.
Colon Cancer WHAT YOU NEED Vitamin D
WHAT IT DOES Got milk? It contains vitamin D, which is associated with a lower risk of
the type of polyp that can lead to colon cancer. Vitamin D is thought to
control the proliferation and growth of cells in the gut, says David
Lieberman, MD, chief of gastroenterology at Portland VA Medical Center and
Oregon Health & Science University and the lead author of a study on colon
cancer. "If cells don't turn over as fast, you may be less likely to have
defects or mutations in the colon," he says.
AIM FOR People who got more than 645 IU of vitamin D a day in the study had
significantly fewer polyps the growths that can turn cancerous.
HOW TO GET IT
Many of us don't get enough vitamin D from foods such as fortified milk, so
you probably need a supplement, especially if you can't tolerate dairy
foods.
NEVER TAKE MORE THAN the UL of 2,000 IU.
What No One Ever Tells You About Vitamins Nutritional supplements are largely unregulated. When it comes to safety and
quality, "you're trusting the manufacturer completely," says Tod Cooperman,
MD, president and founder of the supplement-rating Web site consumer lab.com.
All of which makes us wonder:
Why do vitamins smell so weird? Blame the natural aroma of degrading B
vitamins, which contain sulfur compounds that make them slightly pungent
even while they're still good, says William Obermeyer, PhD,
consumer lab.com's vice president for research.
Do vitamins go bad on the expiration date? It's wise to trust the dates,
which are not required but tend to be listed by more reputable
manufacturers, Cooperman says. For freshness, look for a date that's at
least nine months in the future.
What's in vitamins besides vitamins? Pills contain extras such as coatings,
to prevent degradation, and "flow agents," which make contents easier to
handle during manufacturing. None pose a problem unless you have a rare
allergy to one of them, Obermeyer says.
Are some brands better than others? Definitely. That's why Cooperman began
rating them. There are no guarantees, but the usp seal, from U.S.
Pharmacopeia (which sets manufacturing standards), and the consumerlab.com
seal are good signs. No brand is problem-free, including store brands from
big-name pharmacy chains. One standout is Wal-Mart's Spring Valley line,
whose products are often above average, Cooperman says.
Do kids need to take vitamins? According to the American Academy of
Pediatrics, children who eat a well-balanced diet don't need supplements.
The exceptions: kids who have poor appetites or those whose diets are
erratic. The AAP concedes that children's multivitamins are generally safe,
so your decision should not be too fraught. To prevent overdosing, give
children under age four half a pill, Cooperman advises.
Are children's chewable vitamins loaded with sugar? Most contain small
amounts of sugar or artificial sweetener for taste, but not enough to cause
a child health problems, Cooperman says. A bigger concern is overdosing on
candy like pills; always keep vitamins out of the reach of children.
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